The Bacteria and Archaea represent the most diverse range of organisms on the planet and this is reflect by the many different strategies for extracting DNA from different species. The prepGEM™ Bacteria kit has been shown to be effective on a wide range of species including Gram negative and Gram positive bacteria and clinical isolates. The method uses a patented technology where mesophilic enzymes are mixed with the prepGEM™ thermophilic proteinase (something you cannot do with mesophilic proteinases like proteinase K). The result is a hands-off, closed-tube method that protects the integrity of the sample and safety of the laboratory staff.